Isotretinoin: From Guidelines to Real-Life Clinical Practice
This publication from the Decision Making series explores the role of isotretinoin in the treatment of acne, comparing the main recommendations of European and American guidelines with their application in real-life clinical practice.
The volume examines treatment indications, dosing strategies and therapy personalization, with particular attention to balancing efficacy and tolerability. It also addresses clinical and laboratory monitoring, the management of adverse effects and the available evidence concerning the potential neuropsychiatric risks associated with isotretinoin.
A dedicated section focuses on teratogenic risk management and the regulatory aspects of isotretinoin prescription in Italy, including the Pregnancy Prevention Programme, AIFA documentation and the responsibilities of the healthcare professionals involved. Overall, the publication presents a responsible and personalized approach to isotretinoin therapy, integrating clinical guidelines, scientific evidence and real-world experience.